Read the Medication Guide before you start receiving XEOMIN (Zeo-min) and each time XEOMIN is given to you as there may be new information. The risk information provided here is not comprehensive. To learn more:

Talk to your health care provider or pharmacist Visit www.xeominaesthetic.com to obtain the FDA-approved product labeling Call 1-866-862-1211 Uses XEOMIN is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults for a short period of time (temporary).

It is not known if XEOMIN is safe and effective in children under 18 years of age.


XEOMIN may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems anytime (hours to weeks) after treatment with XEOMIN:

Problems with swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN. People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN. Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems. Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing. These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.

Do not use XEOMIN if you are allergic to XEOMIN or any of the ingredients in XEOMIN (see the end of this Guide for a list of ingredients in XEOMIN), had an allergic reaction to any other botulinum toxin products such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®, BOTOX® COSMETIC), or abobotulinumtoxinA (DYSPORT®) or have a skin infection at the planned injection site.

Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:



Scientific Craftsmanship

NEOCUTIS strives to deliver skincare solutions based on meticulous scientific craftsmanship and is unrelenting in its pursuit to offer premium products with the best skincare ingredients available. NEOCUTIS begins the product development process by seeking a deep understanding of how skin works and the root causes behind concerns such as aging, pigmentation, redness, dehydration and textural skin changes.

After identifying the causes of key skin concerns, NEOCUTIS then sources specific ingredients to create unique formulas for optimal results. If an ingredient does not exist to address a particular skin concern, NEOCUTIS scientists use their skincare expertise to develop novel, benefits-driven ingredients. NEOCUTIS has patented several proprietary ingredients, such as NEO•PEPTIDE 7.5 in its MPC technology, to offer novel skincare solutions.

All the exhaustive effort and care that NEOCUTIS puts into each formula means that its physician partners have the highest quality skincare products to offer consumers. NEOCUTIS consumers can be assured that the products they invest in will truly deliver desired benefits and a luxurious skincare experience.

NEOCUTIS is dedicated to being the most admired, trusted and innovative physician-dispensed skincare brand. NEOCUTIS strives to fulfill this mission by developing exclusive technology platforms based on cutting-edge scientific research. Incorporating targeted technologies into luxurious product formulas enables NEOCUTIS to deliver innovative skincare solutions that address key skincare concerns, including the signs of aging, discoloration, oxidative stress, skin redness and dryness.


+ What skin types should use NEOCUTIS products?

NEOCUTIS products are formulated for all skin types including normal, dry, oily and combination skin. We offer products to address key skincare concerns, including aging, discoloration, oxidative stress, skin dryness and redness. We recommend consulting your physician to learn which NEOCUTIS products are best for your skin type.

+ Do NEOCUTIS products require a prescription?

No, NEOCUTIS products are cosmetic products formulated to help improve the appearance and feel of skin. However, NEOCUTIS products are exclusively available through physicians.

+ Does NEOCUTIS test its products on animals?

No, NEOCUTIS does not test any of its products on animals.

+ How is PSP® obtained?

PSP is well tolerated for topical use. The cells used to initiate PSP production were free of viruses of viral adventitious agents, mycoplasma, bacteria of fungi. PSP is produced under stringent manufacturing procedures similarly than required for a biological drug product by regulatory authorities around the world.

+ What is the exact composition of PSP®?

PSP® is composed of proteins and other processed skin cell constituents obtained after cell disruption. It does not contain cells. Analytical studies on PSP® indicated the presence of numerous growth factors and cytokines.

+ Are products formulated with PSP® safe for topical use?

The BIO•ESSENTIALS™ powered by PSP® are well tolerated for topical use when used as directed.

+ Are NEOCUTIS products formulated with PSP® well tolerated on sensitive or stressed skin?

The BIO•ESSENTIALS™ were formulated for skin tolerability: free of fragrances, color additives and non-comedogenic. The skin tolerability of these products was evaluated during standard dermalogical studies for cosmetic products. However, we recommend that you use these products as directed by your skincare professional.

+ Can NEOCUTIS skincare products be used for wound treatment?

All NEOCUTIS products are for external use only and not for use on wounds.

+ What are the differences between MPC™ and PSP® technologies?

PSP® (Processed Skin Proteins) technology is an optimal blend of human growth factors, cytokines and interleukins to help rejuvenate, energize and nourish the appearance of skin. In consumer studies, the topical application of products with PSP® have been found to significantly reduce the visible signs of skin aging such as fine lines and wrinkles, roughness and uneven skin tone.

In contrast, MPC™ (Micro Protein Complex) technology is a synthetic alternative to growth factors to help address aging concerns like skin elasticity, firmness, fine lines and wrinkles. MPC is the latest technology innovation by NEOCUTIS inspired by a new understanding of the role the extracellular matrix plays in skin aging. Recent research suggests that the change in five key components of the ECM – Collagens I, III, VII, Elastin and Hyaluronic Acid – are responsible for the visible signs of aging. MPC is a new generation of skin-rejuvenating micro-proteins that target the five key components of the ECM. In a consumer study, an MPC™ formulation was shown to significantly impact firmness, elasticity, fine lines and wrinkles, skin roughness and the appearance of pores.

+ Where can I buy authentic NEOCUTIS products online?

Please consult our NeoFinder to find a NEOCUTIS skincare provider near you.

If you choose to buy online please contact customer service at 866.636.2884 for a list of authorized online retailers.

NEOCUTIS cannot attest to the authenticity of product purchases at any unauthorized online retailers and does not take any responsibility for customer dissatisfaction.

+ Where can I earn NEOCUTIS Swiss Rewards loyalty points?

The NEOCUTIS Swiss Rewards program is only available at participating healthcare provider offices and excludes Internet providers. Please consult our NEOFINDER to find a NEOCUTIS skincare provider near you.